On Air Now Overnights on Star Radio Midnight - 6:00am
Now Playing Mica Paris I Never Felt Like This Before

Cambridge patients trial new Parkinson's drug

Photo: Parkinson's affects 150,000 people in the UK

Addenbrooke’s Hospital is trialling a new drug aimed at treating Parkinson’s disease.

Parkinson’s affects thousands of people in the UK but there is currently no way to stop or slow its progression.

Research suggests that inflammation in the brain might be important to understanding Parkinson’s and this is a target of interest for new therapies.

Now, Cambridge researchers alongside Addenbrooke's patients have teamed up to investigate the potential of an anti-inflammatory drug called dapansutrile.

It is being led by Dr Caroline Williams-Gray:

"There is a pressing need for a specific treatment, such as dapansutrile, which targets the most relevant aspects of the immune activation pathway in Parkinson’s without causing general immunosuppression and leading to unwanted side effects.

"In this trial, we aim to determine dapansutrile’s safety and tolerability in people with Parkinson’s, and to establish whether the treatment can reduce inflammation in the brain. 

"We will also investigate whether this results in a positive effect on clinical symptoms and disease progression."

The trial will involve 36 people with Parkinson’s who will be treated with dapansutrile tablets for up to 12 months. 

In this early phase trial, the main aims will be to establish that the drug is safe in Parkinson’s, and to determine whether it reduces inflammation in the brain.  

Parkinson’s symptoms include tremor, stiffness and slowness of movement, and arises after substantial loss of the dopamine-producing cells in an area of the brain known as the substantia nigra. 

The movement problems can be accompanied by anxiety, sleep disturbance, gut symptoms, cognitive problems and dementia.

More from Local News

Get The App

Take Star Radio with you wherever you go and listen to us live. Interact with the studio and call, email, text and Tweet us all directly from within the app.

Weather

  • Fri

    Light rain shower

    13°C

  • Sat

    Low-level cloud

    10°C

  • Sun

    Low-level cloud

    11°C

  • Mon

    Medium-level cloud

    11°C